About effective and approved means to combat head lice

In accordance with the work program of the Research Institute of Disinfectology of Rospotrebnadzor and the All-Russian Scientific and Methodological Center for Nonspecific Prevention of Infectious Diseases and Monitoring of the Resistance of Biological Agents to Disinfectants, which operates on its basis, work has been completed to study the sensitivity to insecticides of body lice and head lice.

It has been established that high resistance of lice to pyrethroids has developed on the territory of the Russian Federation - lice resistant to permethrin make up more than 95% of micropopulations collected in the country. None of the permethrin-based pediculicidal agents provides 100% acute action; there is no ovicidal effect.

A study of the sensitivity to insecticides of body and head lice from Moscow, St. Petersburg, Tambov, Kursk, Kazan, Novosibirsk, Khabarovsk, Khanta-Mansiysk and other cities by specialists from the Federal Budgetary Institution Research Institute of Disfectology of Rospotrebnadzor was carried out for 9 years.

The molecular genetic method has shown that lice with mutations that determine a decrease in the sensitivity of the nervous system to the action of pyrethroids are widespread in all local populations of head and body lice in all federal districts of Russia.

Currently, in the Register of State Registration Certificates (unified form of the Customs Union, Russian part), the share of pyrethroid-based products is about 40%.

At the same time, products based on substances with a different mechanism of action than pyrethroids remain effective: benzyl benzoate, organophosphorus compounds (malathion, fenthion), dimethicones, isopropyl myristate, clearol, substances of plant origin (anise, clove oils, neem oil, and some others) (Appendix 1 and 2).

In order to limit and completely eliminate the use of pediculicides based on pyrethroids for the treatment of head, body, and pubic lice, I ask you to use this information when monitoring the circulation of pediculicides, and also when working with the population and the media. Lists of approved pediculicides are presented in Appendices 1-5.

Annex 1

PRODUCTS FOR DESTROYING PYRETHROID-RESISTANT HEAD AND PUBIC LICE

Polydimethylsiloxanes

• pediculicide "HEDRIN" 77.99.1.2.U.4547.6.10 dated 06/29/2010 dimethicone - 4% "Thornton and Ross Ltd.", "Thornton and Ross Ireland Ltd." (Great Britain)
• pediculicidal agent “D-95” of the trademark “911 Your Rescue Service” RU.77.99.88.002.E.002023.04.17 dated 04/27/2017 dimethicone 87.7%; CJSC "TWINS Tech", (Russian Federation)
• pediculicidal agent "Nyuda®" RU.77.99.88.002.E.012895.12.14 dated 12/29/2014 dimethicone 92%, Germany
• pediculicidal agent "Paranit® Sensitive" (Paranit® Sensitive) RU.77.99.88.002.E.004749.06.14 dated 06.20.2014 oxyphthyrin complex, including dimethicone -4% "Cefaro Ireland Limited", (Ireland) and "Megenix Benelux" » (Belgium) «Laboratories Wilson» (France)
• pediculicidal product “Hedrin Once (Hedrin Vance)” in two forms Liquid Gel (liquid gel), Spray Gel (spray gel) RU.77.99.88.002.E.010406.11.15 dated November 26, 2015 dimethicone, 4%, nerolidol, 2% ; "Thornton & Ross Ltd", (UK)
• pediculicidal agent “Full Marks” (“Full Marks”), RU.77.99.88.002.E.000357.01.18 dated 01/26/2018 isopropyl myristate -50%, cyclomethicone 50% “Reckit Benckiser Healthcare” (UK)
• pediculicidal agent “Nitolic” (“Nitolic”), RU.77.99.88.002.E.000462.02.18 dated 02/01/2018 isopropyl myristate -72.5%, “ICB Pharma” (Poland)
• pediculicidal agent - “Clean Life” RU.77.99.88.002.E.005564.07.13 from 07/08/2013 polydimethylsiloxanes, 47%; LLC "NPO "VELT", (Russian Federation)
• pediculicidal product "Duranit anti-pediculosis lotion for hair" RU.77.99.88.002.E.005135.06.13 from 06.28.2013 dimethicone - 6%, cyclopentaxyloxane - 94%, "Drog Ekza Tibbi Malzeme" (Turkey)
• pediculicide "PARADISE ULTRA" RU.77.99.88.002.E.002037.05.18 dated 05/21/2018 dimethicone, 4%, isoparaffins, 96%, Mirrolla LLC, (Russian Federation)

Mineral oils

• pediculicidal agent “Shampoo “Deparazin® Ultra” RU.77.99.88.002.E.000369.01.16 from 01/28/2016 petroleum jelly, 56.5%; BIOPHARMRUS LLC, (Russian Federation)
• pediculicidal product “Shampoo “Pedikulen Ultra” RU.77.99.88.002.E.008118.09.14 from 09.19.2014 petroleum jelly - 55%; BIOPHARMUS LLC, (Russian Federation)
• pediculicidal product Paranit® Shampoo (Paranit® Shampoo) RU.77.99.88.002.E.012487.12.14 dated 12/22/2014 clearol (mineral oil) - 69.25%; Chefaro Ireland Limited, (Ireland) Chefaro Ireland Limited, Ireland (Ireland) and Megenix Benelux (Belgium) Bittner Pharma LLC, (Russian Federation)
• pediculicidal product Paranit® Lotion (“Paranit® Lotion”) RU.77.99.88.002.E.012486.12.14 dated December 22, 2014 isopar (mineral oil) - 96%, dimethicone - 4%, Chefaro Ireland Limited, (Ireland) Chefaro Ireland Limited, Ireland (Ireland) and Megenix Benelux (Belgium) Bittner Pharma LLC, (Russian Federation)
• pediculicidal product Paranit® Spray (“Paranit® Spray”) RU.77.99.88.002.E.012485.12.14 dated December 22, 2014 isopar (mineral oil) - 96%, dimethicone - 4%, Megenix Benelux (Belgium) LLC " Bittner Pharma", (Russian Federation)

Benzyl benzoate

• pediculicidal agent "Foxilon spray" RU.77.99.21.002.E.011175.07.12 dated 07/05/2012 benzyl benzoate, 20% NPC "FOX & Co" LLC, (Russian Federation)
• pediculicidal agent "Foxilon lotion" RU.77.99.01.002.E.027606.07.11 dated 07/18/2011 benzyl benzoate, 20% Scientific-Production LLC, (Russian Federation)

Neem oil

• pediculicidal product "Leisner" RU.77.99.88.002.E.001143.03.17 from 03/09/2017 neem oil 10%, "Pronova Laboratories BiVi", (Netherlands)

Essential oils

• pediculicidal agent “Paranit” RU.77.99.27.002.E.043822.10.11 dated 10/20/2011 anise oil (in terms of trans-anethole), 15%, “Teva Pharmaceutical Industries”, (Israel)
• insecticidal agent "MEDILIS-bio for lice" RU.77.99.37.002.E.002102.02.11 dated 02/09/2011 clove oil - 10% LLC "Laboratory MediLIS", (Russian Federation)
• pediculicidal product "Pedikulen® Ultra" RU.77.99.88.002.E.007718.08.13 dated 08/27/2013 anise oil - 6 LLC "BIOPHARMUS", % (Russian Federation)

Alcohols

• pediculicidal product "Hedrin Treat & Go" in three forms Lotion (lotion), Spray (spray), Mousse (mousse) RU.77.99.88.002.E.010405.11.15 dated November 26, 2015 1.2 octanediol , 5%, caprylic/capric glycerides (PEG 6) 15%; Thornton & Ross Ltd. (Great Britain)

Organophosphorus compounds

• insectoacaricidal agent "Sulfox" RU.77.99.21.002.E.012445.08.12 dated 08/10/2012 fenthion 20% k.e. LLC NPC "FOX & Co", (Russian Federation)
• insectoacaricidal agent “Dobrokhim FOS” RU.77.99.88.002.E.006398.08.13 dated 08/05/2013, fenthion 20% e.e. LLC "Dobrokhim", (Russian Federation)
• insectoacaricidal agent "Medilis-super" RU.77.99.88.002.E.017368.12.12 dated 12/25/2012 24% e.e. water-based fenthion LLC "Laboratory MediLIS", (Russian Federation)
• insectoacaricidal agent Medilis-Permifen" RU.77.99.88.002.E.008546.10.13 dated 10.23.2013 20% e.e. (fenthion - 16%, permethrin - 4%) LLC "Laboratory MediLIS", (Russian Federation)
• insecticidal agent "Forsyth - anti-louse" RU.77.99.21.002.E.012959.08.12 dated 08.28.2012 10% q.e. mixtures of fenthion and permethrin. (fenthion - 7%, permethrin - 3%) Alina Nova Prof LLC, (Russian Federation)
• insectoacaricidal agent “Clinch” 77.99.23.2.U.341.1.10 dated 01/26/2010 mixture of fenthion and permethrin 20% a.e. (fenthion - 7%, permethrin - 13%) Dobrokhim LLC, (Russian Federation)
• insectoacaricidal agent "Medilis - Malathion" RU.77.99.88.002.E.005275.06.13 dated 06.28.2013 40% e.e., malathion LLC "Laboratory MediLIS", (Russian Federation)
• insectoacaricidal agent “Dobrokhim M” RU.77.99.88.002.E.000104.01.14 dated 01/15/2014 malathion 57% ke., Dobrokhim LLC, (Russian Federation)
• pediculicidal product “Veltotrin Lotion” RU.77.99.19.002.E.006964.04.12 dated 04/23/2012 permethrin, 1%, malathion, 0.3%; LLC "NPO "VELT", (Russian Federation)

Appendix 2

It is possible to defeat parasites!

Antiparasitic Complex® - Reliable and safe removal of parasites in 21 days!

• The composition includes only natural ingredients;
• Does not cause side effects;
• Absolutely safe;
• Protects the liver, heart, lungs, stomach, skin from parasites;
• Removes waste products of parasites from the body.
• Effectively destroys most types of helminths in 21 days.

There is now a preferential program for free packaging. Read expert opinion.

Read further:

Sanitation for pediculosis: algorithm for treating the patient and the room

Shampoo for head lice: list of the best products for preventing head lice

How long do lice live on clothes and outside a person’s head?

What lice and nits look like on human hair, in adults and children

Echinococcosis and Alveococcosis: main differences, routes of infection and symptoms

Pediculosis in a child: main signs and treatment methods

CONTENTS OF THE PACK FOR ANTI-PEDICULOSIS MEASURES

1. An oilcloth or cotton bag for collecting the patient's belongings.
2. Galvanized bucket or tray for burning or disinfecting hair.
3. Oilcloth drape.
4. Rubber gloves.
5. Scissors.
6. A fine comb (preferably metal).
7. Hair clipper.
8. Alcohol lamp.
9. Headscarves (2-3 pieces).
10. Cotton wool.
11. Table vinegar or 5-10% acetic acid.
12. Magnifier
13. Means for the destruction of head and pubic lice that have a 100% ovicidal effect (ovicides) with a single treatment (“Medilis-bio”, “Foxilon lotion”, “Para-PLUS”, emulsion concentrates based on fenthion (“Sulfox”, “Medilis- super”, etc.).
14. Products that have an incomplete ovicidal effect, which require double treatment with an interval of 7-10 days (Foxilon-spray, Paranit lotion, Paranit spray, Nyuda, etc.).
15. Products for the destruction of body lice (emulsion concentrates based on fenthion - “Sulfox”, “Medilis-super”, “Clinch”, “Foresight-anti-louse”, “Dobrokhim FOS”, malathion “Dobrokhim M”, “Medilis - Malathion”).
16. Means for disinfestation of premises (con, “Medilis-super”, “Clinch”, “Foresight-anti-louse”, “Dobrokhim FOS”, “Medilis-permifen”, etc.).

Appendix 4

Classic and modern composition, are there any differences?

The modern composition of anti-pediculosis styling differs from the classic one. What should include:

• yellow package marked “B”;
• protective overalls and respirator mask;
• shoe covers.

The composition should contain several means to combat parasites on the human body and 1 or 2 drugs for disinfecting premises.

Are there any differences in treatment with pediculocidal agents for medical personnel, patients, in hospitals, hospitals, emergency rooms, kindergartens and schools.

PROHIBIT USE COMPLETELY

Ready-to-use pediculicides based on pyrethroids (permethrin, tetramethrin, d-phenothrin):

• pediculicidal product "Pedilin" in the form of shampoo RU.77.99.27.002.E.001414.01.12 dated 01/20/2012 permethrin 1% DV; KRKA, (Slovenia)
• pediculicidal agent “Higia” for the fight against head and pubic lice (in the form of shampoo) RU.77.99.23.002.E.013494.05.11 dated 05/10/2011 permethrin 1% DV; JSC "Medika" (Bulgaria)
• pediculicidal agent “Nittifor-cream” RU.77.99.01.002.E.041440.10.11 dated 10/05/2011 permethrin 1% DV; "Pharmaceutical plant Teva Private Co. Ltd.", (Hungary)
• pediculicidal shampoo “Veda” RU.77.99.01.002.E.039178.09.11 dated 09/22/2011 permethrin 0.4% DV; CJSC Experimental-Production (CJSC DDD), (Russian Federation)
• pediculicidal agent "Veda-2" RU.77.99.01.002.E.000438.01.11 dated 01/19/2011 permethrin 0.5% DV, Experimental-Production CJSC (DDD CJSC), (Russian Federation)
• pediculicidal agent “DIS” RU.77.99.01.002.E.002699.02.11 dated 02/15/2011 permethrin 0.7% DV, tetramethrin 0.5% DV, pyriproxyfen 0.05% DV; CJSC Experimental-Production (CJSC DDD), (Russian Federation)
• pediculicidal agent "Medifox - pediculicidal gel" RU.77.99.55.002.E.032909.08.11 dated 08/17/2011 permethrin 1% DV; LLC NPC "FOX & Co", (Russian Federation)
• pediculicidal agent “Samarovka-lotion” RU.77.99.01.002.E.003320.02.11 dated 02/21/2011 permethrin 0.2% DV; Samarovo LLC, (Russian Federation)
• pediculicidal product “Hygea - pediculicidal shampoo” RU.77.99.01.002.E.001247.02.11 dated 02/01/2011 permethrin 0.9% DV; Samarovo LLC, (Russian Federation)
• pediculicidal agent “Mirrolla permethrin “FORA+” RU.77.99.88.002.E.003250.04.14 dated 04/24/2014 permethrin 1.5% DV; LLC "Mirrolla" (Russian Federation)
• insecticidal agent "Zitol-spray" RU.77.99.27.002.E.050158.12.11 from 07.12.2011 permethrin 0.3% DV JSC "NPF "Ekoprom", (Russian Federation)
• insecticidal soap “VITAR” RU.77.99.01.002.E.040057.09.11 dated 09/27/2011 permethrin 0.5% DV; CJSC, (Russian Federation)

Appendix 5

Examination for lice

Medical workers are required to conduct head lice inspections in preschool educational institutions once a month, at school after the holidays, and selectively by class every month. At enterprises, institutions, and organizations, mandatory inspections must also be carried out twice a year.

According to the order of the Ministry of Health, it is mandatory to carry out a preventive examination of patients at the sanitary inspection station when placing a patient for inpatient treatment or in a maternity hospital. The inspection procedure involves the use of a fine-toothed comb, a magnifying glass or a magnifying glass.